Pulmonary Surfactant-Associated Protein C

**Definition:** A pulmonary surfactant associated protein that plays a role in alveolar stability by lowering the surface tension at the air-liquid interface. It is a membrane-bound protein that constitutes 1-2% of the pulmonary surfactant mass. Pulmonary surfactant-associated protein C is one of the most hydrophobic peptides yet isolated and contains an alpha-helical domain with a central poly-valine segment that binds to phospholipid bilayers.

**Tree numbers:** - D12.776.543.717 - D12.776.816.750 - D12.776.823.186

**Synonyms:** - Pulmonary Surfactant Protein C - Pulmonary Surfactant-Associated Protein SP-C - SP-C protein - Surfactant Polypeptide SP-C