Polypyrimidine Tract-Binding Protein

**Definition:** A RNA-binding protein that binds to polypyriminidine rich regions in the INTRONS of messenger RNAs. Polypyrimidine tract-binding protein may be involved in regulating the ALTERNATIVE SPLICING of mRNAs since its presence on an intronic RNA region that is upstream of an EXON inhibits the splicing of the exon into the final mRNA product.

**Tree numbers:** - D12.776.157.725.829.250 - D12.776.664.962.829.250

**Synonyms:** - pPTB - PTB Protein - PTB Splicing Factor - p57 Cytoplasmic RNA-Binding Protein