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D038982Level 7

Integrin alpha2beta1

**Definition:** An integrin found on fibroblasts, platelets, endothelial and epithelial cells, and lymphocytes where it functions as a receptor for COLLAGEN and LAMININ. Although originally referred to as the collagen receptor, it is one of several receptors for collagen. Ligand binding to integrin alpha2beta1 triggers a cascade of intracellular signaling, including activation of p38 MAP kinase.

**Tree numbers:** - D09.400.430.890.625.298 - D12.776.395.550.625.298 - D12.776.543.550.625.298 - D12.776.543.750.685.200 - D12.776.543.750.705.408.530.249 - D12.776.543.750.705.408.850.199 - D12.776.543.750.705.675.352 - D12.776.543.750.705.876.280

**Synonyms:** - CD49b-CD29 - VLA-2 - Glycoprotein Ia-IIa - Platelet Membrane Glycoprotein Heterodimer Ia-IIa - alpha2beta1Integrin - Very Late Antigen-2

GET/api/v1/systems/mesh/nodes/D038982
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