Integrin alpha4beta1

**Definition:** Integrin alpha4beta1 is a FIBRONECTIN and VCAM-1 receptor present on LYMPHOCYTES; MONOCYTES; EOSINOPHILS; NK CELLS and thymocytes. It is involved in both cell-cell and cell- EXTRACELLULAR MATRIX adhesion and plays a role in INFLAMMATION, hematopoietic cell homing and immune function, and has been implicated in skeletal MYOGENESIS; NEURAL CREST migration and proliferation, lymphocyte maturation and morphogenesis of the PLACENTA and HEART.

**Tree numbers:** - D09.400.430.890.200.625.347 - D12.776.395.550.200.625.347 - D12.776.543.550.200.625.347 - D12.776.543.750.705.408.530.500 - D12.776.543.750.705.408.850.299 - D12.776.543.750.705.877.347 - D23.050.301.350.625.347

**Synonyms:** - VLA-4 - Integrin alpha(4)beta(1) - Integrin Heterodimer alpha4beta1 - CD49d-CD29 - Very Late Antigen-4 - alpha4beta1 Integrin - Very Late Activation Antigen-4