Integrin alpha6beta4

**Definition:** This intrgrin is a key component of HEMIDESMOSOMES and is required for their formation and maintenance in epithelial cells. Integrin alpha6beta4 is also found on thymocytes, fibroblasts, and Schwann cells, where it functions as a laminin receptor (RECEPTORS, LAMININ) and is involved in wound healing, cell migration, and tumor invasiveness.

**Tree numbers:** - D12.776.543.750.705.408.460.170 - D12.776.543.750.705.876.750

**Synonyms:** - alpha(6)beta(4) Integrin - alpha6 beta4 Integrin - Integrin alpha(6),beta(4) - Laminin-5 Receptor (alpha6beta4 Integrin) - TSP-180 - Tumor Specific Protein-180 Complex - alpha(6)beta(4) Epithelial Integrin - A9 Antigen