Steroid 16-alpha-Hydroxylase

**Definition:** A liver microsomal cytochrome P450 enzyme that catalyzes the 16-alpha-hydroxylation of a broad spectrum of steroids, fatty acids, and xenobiotics in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme is encoded by a number of genes from several CYP2 subfamilies.

**Tree numbers:** - D08.244.453.915.737 - D08.811.682.690.708.170.915.737 - D12.776.422.220.453.915.737

**Synonyms:** - 16-alpha Hydroxylase - 16alpha-Hydroxylase - Estrogen 16-alpha Hydroxylase - Estrone 16-alpha Hydroxylase - Estrone-3-sulfate 16-alpha Hydroxylase - Steroid 16alpha-Hydroxylase - Estradiol 16-alpha Hydroxylase - Progesterone-16-alpha-Hydroxylase - Progesterone 16 alpha-Hydroxylase - Testosterone 16-alpha Hydroxylase - Cytochrome P-450(16 alpha) - Testosterone 16alpha Hydroxylase - Progesterone 16-alpha-Hydroxylase