Cleavage And Polyadenylation Specificity Factor

**Definition:** An RNA-binding protein that recognizes the AAUAAA RNA SEQUENCE at the 3' end of MRNA. It contains four subunits of 30, 73, 100 and 160 kDa molecular size and combines with CLEAVAGE STIMULATION FACTOR to form a stable complex with mRNA that directs the 3' cleavage and polyadenylation reaction.

**Tree numbers:** - D12.776.157.725.124.240 - D12.776.664.962.444.240

**Synonyms:** - CPSF Protein - Cleavage-Polyadenylation Specificity Factor