Cleavage Stimulation Factor

**Definition:** A RNA-binding protein that stimulates the cleavage of the 3' end of MRNA near the POLYADENYLATION site. It is a heterotrimer of 55-, 64- and 77-kDa subunits and combines with CLEAVAGE STIMULATION FACTOR to form a stable complex with mRNA that directs the 3' cleavage and polyadenylation reaction.

**Tree numbers:** - D12.776.157.725.124.249 - D12.776.664.962.444.249

**Synonyms:** - CstF Protein