Eukaryotic Initiation Factor-3

**Definition:** A multisubunit eukaryotic initiation factor that contains at least 8 distinct polypeptides. It plays a role in recycling of ribosomal subunits to the site of transcription initiation by promoting the dissociation of non-translating ribosomal subunits. It also is involved in promoting the binding of a ternary complex of EUKARYOTIC INITIATION FACTOR-2; GTP; and INITIATOR TRNA to the 40S ribosomal subunit.

**Tree numbers:** - D12.776.835.725.868.437

**Synonyms:** - EIF-3 - EIF3 - Eukaryotic Peptide Initiation Factor-3 - Peptide Initiation Factor EIF-3