Prokaryotic Initiation Factor-1

**Definition:** The smallest of the three prokaryotic initiation factors with a molecular size of approximately 8 kD. It binds near the A-site of the 30S subunit of RIBOSOMES and may play a role in preventing premature addition of aminoacyl-tRNA-linked PEPTIDE ELONGATION FACTOR TU to the ribosome during the initiation of a peptide chain (PEPTIDE CHAIN INITIATION, TRANSLATIONAL).

**Tree numbers:** - D12.776.835.725.934.374

**Synonyms:** - Initiation Factor IF-1 - Peptide Initiation Factor IF-1 - Peptide Initiation Factor-1, Prokaryotic - Prokaryotic Peptide Initiation Factor-1