Eukaryotic Initiation Factor-5

**Definition:** A eukaryotic initiation factor that interacts with the 40S initiation complex and promotes the hydrolysis of the bound GTP. The hydrolysis of GTP causes the release of EUKARYOTIC INITIATION FACTOR-2 and EUKARYOTIC INITIATION FACTOR-3 from the 40S subunit and the subsequent joining of the 60S ribosomal subunit to the 40S complex to form the functional 80S initiation complex

**Tree numbers:** - D12.644.360.325.150.300 - D12.776.476.325.150.300 - D12.776.835.725.868.750

**Synonyms:** - EIF-5 - Peptide Initiation Factor EIF-5 - Eukaryotic Peptide Initiation Factor-5