Semaphorin-3A

**Definition:** The prototypical and most well-studied member of the semaphorin family. Semaphorin-3A is an axon-repulsive guidance cue for migrating neurons in the developing nervous system. It has so far been found only in vertebrates, and binds to NEUROPILIN-1/plexin complex receptors on growth cones. Like other class 3 semaphorins, it is a secreted protein.

**Tree numbers:** - D12.644.276.923.374 - D12.776.467.923.374 - D23.529.923.374

**Synonyms:** - Sem D - Semaphorin D - Collapsin - Sema3A - Semaphorin 3A - Collapsing Factor - Collapsin-1