Vascular Endothelial Growth Factor Receptor-1

**Definition:** A 180-kDa VEGF receptor found primarily in endothelial cells that is essential for vasculogenesis and vascular maintenance. It is also known as Flt-1 (fms-like tyrosine kinase receptor-1). A soluble, alternatively spliced isoform of the receptor may serve as a binding protein that regulates the availability of various ligands for VEGF receptor binding and signal transduction.

**Tree numbers:** - D08.811.913.696.620.682.725.400.950.100 - D12.776.476.568.400.950.100 - D12.776.543.750.630.750.100 - D12.776.543.750.750.400.910.100

**Synonyms:** - FLT1 Receptor Tyrosine Kinase - VEGF Receptor flt-1 Protein - VEGF Receptor, FLT - FLT1 RTK - fms-Like Tyrosine Kinase - Proto-Oncogene Protein flt - VEGFR-1