Receptor, TIE-2

**Definition:** A TIE receptor tyrosine kinase that is found almost exclusively on ENDOTHELIAL CELLS. It is required for both normal embryonic vascular development (NEOVASCULARIZATION, PHYSIOLOGIC) and tumor angiogenesis (NEOVASCULARIZATION, PATHOLOGIC).

**Tree numbers:** - D08.811.913.696.620.682.725.400.925.500 - D12.776.476.568.400.925.500 - D12.776.543.750.630.687.500

**Synonyms:** - TIE2 Tyrosine Kinase - TIE-2 Receptor Tyrosine Kinase - TIE-2-RTK - Tie2 Receptor - Tek Receptor - Angiopoietin Receptor Tie-2