Methylenetetrahydrofolate Reductase (NADPH2)

**Definition:** A flavoprotein amine oxidoreductase that catalyzes the reversible conversion of 5-methyltetrahydrofolate to 5,10-methylenetetrahydrofolate. This enzyme was formerly classified as EC 1.1.1.171.

**Tree numbers:** - D08.811.682.662.290 - D12.776.331.775

**Synonyms:** - 5,10-Methylenetetrahydrofolate Reductase (NADPH) - Methylene Tetrahydrofolate Reductase - Methylene-THF Reductase (NADPH) - Methylenetetrahydrofolate Reductase - Methylenetetrahydrofolate Reductase (NADPH)