Phosphatidylinositol Diacylglycerol-Lyase

**Definition:** A phosphorus-oxygen lyase found primarily in BACTERIA. The enzyme catalyzes the cleavage of a phosphoester linkage in 1-phosphatidyl-1D-myo-inositol to form 1D-myo-inositol 1,2-cyclic phosphate and diacylglycerol. The enzyme was formerly classified as a phosphoric diester hydrolase (EC 3.1.4.10) and is often referred to as a TYPE C PHOSPHOLIPASES. However it is now known that a cyclic phosphate is the final product of this enzyme and that water does not enter into the reaction.

**Tree numbers:** - D08.811.277.352.640.700.700.500 - D08.811.520.650.800

**Synonyms:** - 1-Phosphatidylinositol Phosphodiesterase - Monophosphatidylinositol Phosphodiesterase