Receptor, Serotonin, 5-HT1B

**Definition:** A serotonin receptor subtype found at high levels in the BASAL GANGLIA and the frontal cortex. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1D RECEPTOR. It is particularly sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigraine effect.

**Tree numbers:** - D12.776.543.750.670.800.100.150 - D12.776.543.750.695.800.100.150 - D12.776.543.750.720.670.100.500 - D12.776.543.750.720.850.100.150

**Synonyms:** - 5-HT1B Receptor - 5-Hydroxytryptamine 1B Receptor - 5-Hydroxytryptamine 1B Receptors - Receptor, 5-Hydroxytryptamine 1B - Serotonin 1B Receptor - 5-HT(1B) Receptor - 5-HT1Dbeta Receptor - Receptor, Serotonin Type 1Dbeta - Serotonin 1Dbeta Receptors - Serotonin 1Dbeta Receptor - Serotonin 1D Beta Receptor - 5-HT(1Dbeta) Receptor