Receptor, PAR-1

**Definition:** A thrombin receptor subtype that couples to HETEROTRIMERIC GTP-BINDING PROTEINS resulting in the activation of a variety of signaling mechanisms including decreased intracellular CYCLIC AMP, increased TYPE C PHOSPHOLIPASES and increased PHOSPHOLIPASE A2.

**Tree numbers:** - D09.400.430.890.625.800.790 - D12.776.395.550.625.800.790 - D12.776.543.550.625.800.790 - D12.776.543.750.695.875.500 - D12.776.543.750.705.675.892.790 - D12.776.543.750.750.850.399 - D12.776.543.750.792.500.500

**Synonyms:** - Protease-Activated Receptor 1 - PAR-1 Receptor - PAR1 Receptor - Proteinase-Activated Receptor 1