S-Phase Kinase-Associated Proteins

**Definition:** A family of structurally-related proteins that were originally identified by their ability to complex with cyclin proteins (CYCLINS). They share a common domain that binds specifically to F-BOX MOTIFS. They take part in SKP CULLIN F-BOX PROTEIN LIGASES, where they can bind to a variety of F-BOX PROTEINS.

**Tree numbers:** - D12.776.157.743

**Synonyms:** - Skp Domain Proteins - Skp Domain Protein - S-Phase Kinase Associated Protein