beta-Mannosidase

**Definition:** An enzyme that catalyzes the hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides. The enzyme plays a role in the lysosomal degradation of the N-glycosylprotein glycans. Defects in the lysosomal form of the enzyme in humans result in a buildup of mannoside intermediate metabolites and the disease BETA-MANNOSIDOSIS.

**Tree numbers:** - D08.811.277.450.625.750

**Synonyms:** - beta-D-Mannosidase - beta-Mannanase - manA protein (beta-Mannosidase)