3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)

**Definition:** A 3-hydroxysteroid dehydrogenase which catalyzes the reversible reduction of the active androgen, DIHYDROTESTOSTERONE to 5 ALPHA-ANDROSTANE-3 ALPHA,17 BETA-DIOL. It also has activity towards other 3-alpha-hydroxysteroids and on 9-, 11- and 15- hydroxyprostaglandins. The enzyme is B-specific in reference to the orientation of reduced NAD or NADPH.

**Tree numbers:** - D08.811.682.047.436.350.100 - D08.811.682.047.820.186

**Synonyms:** - 3 alpha-Hydroxysteroid Dehydrogenase - 3 alpha-Hydroxysteroid Dehydrogenase (B-Specific) - 3 alpha-Hydroxysteroid Oxidoreductase - 3alpha-Hydroxysteroid Dehydrogenase (B-specific)