Matrix Attachment Regions

**Definition:** Regions of the CHROMATIN or DNA that bind to the NUCLEAR MATRIX. They are found in INTERGENIC DNA, especially flanking the 5' ends of genes or clusters of genes. Many of the regions that have been isolated contain a bipartite sequence motif called the MAR/SAR recognition signature sequence that binds to MATRIX ATTACHMENT REGION BINDING PROTEINS.

**Tree numbers:** - G02.111.570.080.534 - G05.360.080.534

**Synonyms:** - MAR Elements - Matrix-Attached Regions - SAR Elements - Scaffold Attachment Regions - Scaffold-Attached Regions