Pregnancy-Associated alpha 2-Macroglobulins

**Definition:** Large (>160 kDa) glycoproteins with electrophoretic mobility of ALPHA-GLOBULINS, found in high concentration in the plasma of PREGNANT PEOPLE but also in a number of species including mouse, rat, and others (ALPHA-MACROGLOBULINS). In humans, they are always present in the circulation and are nonspecific inhibitors of PROTEINASES, similar to COMPLEMENT PROTEINS (C3; C4; C5).

**Tree numbers:** - D12.776.124.790.720.100.500 - D12.776.780.675

**Synonyms:** - alpha(2)-PAG - alpha2-PAG - PAAG - Pregnancy-Associated alpha 2-Globulins - Pregnancy-Associated alpha 2-Glycoproteins