DNA Glycosylases

**Definition:** A family of DNA repair enzymes that recognize damaged nucleotide bases and remove them by hydrolyzing the N-glycosidic bond that attaches them to the sugar backbone of the DNA molecule. The process called BASE EXCISION REPAIR can be completed by a DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE which excises the remaining RIBOSE sugar from the DNA.

**Tree numbers:** - D08.811.074.249 - D08.811.277.450.430.099

**Synonyms:** - DNA Glycosylase - DNA N-glycosidase