Proprotein Convertase 1

**Definition:** A CALCIUM-dependent endopeptidase that has specificity for cleavage at ARGININE that is near paired basic residues. It cleaves a variety of prohormones including PRO-OPIOMELANOCORTIN; PRORENIN; proenkephalins; prodynorphin; prosomatostatin; and PROINSULIN.

**Tree numbers:** - D08.811.277.656.300.760.640 - D08.811.277.656.837.500 - D08.811.277.656.959.350.640

**Synonyms:** - PC3 Endoprotease - PC3 Prohormone Convertase - Neuroendocrine Convertase PC1 - Prohormone Convertase 1 - Proprotein Convertase SPC3 - Proinsulin Convertase 1 - Prohormone Convertase 3 - Prohormone Convertase, PC1 - PC1 Prohormone Convertase - PC1 Endoprotease