3-Isopropylmalate Dehydrogenase

**Definition:** An NAD+ dependent enzyme that catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate to 3-carboxy-4-methyl-2-oxopentanoate. It is involved in the biosynthesis of VALINE; LEUCINE; and ISOLEUCINE.

**Tree numbers:** - D08.811.682.047.820.193

**Synonyms:** - beta-IPM Dehydrogenase - beta-Isopropylmalate Dehydrogenase