Complement C4b-Binding Protein

**Definition:** A serum protein that regulates the CLASSICAL COMPLEMENT ACTIVATION PATHWAY. It binds as a cofactor to COMPLEMENT FACTOR I which then hydrolyzes the COMPLEMENT C4B in the CLASSICAL PATHWAY C3 CONVERTASE (C4bC2a).

**Tree numbers:** - D12.776.124.486.274.920.662

**Synonyms:** - C4b-C3b Inactivator Cofactor - C4bC3bINA-Cofactor - C4b-Binding Protein - Complement C3b-C4b Inactivator Cofactor - Complement Component 4b-Binding Protein - Complement 4b Binding Protein