Retinoblastoma-Like Protein p130

**Definition:** A negative regulator of the CELL CYCLE that undergoes PHOSPHORYLATION by CYCLIN-DEPENDENT KINASES. RBL2 contains a conserved pocket region that binds E2F4 TRANSCRIPTION FACTOR and E2F5 TRANSCRIPTION FACTOR. RBL2 also interacts with viral ONCOPROTEINS such as POLYOMAVIRUS TUMOR ANTIGENS; ADENOVIRUS E1A PROTEINS; and PAPILLOMAVIRUS E7 PROTEINS.

**Tree numbers:** - D12.776.624.776.735 - D12.776.660.794 - D12.776.744.755

**Synonyms:** - RBL2 Protein - Retinoblastoma Like Protein p130 - Retinoblastoma-Like Protein 2