Complement C1 Inhibitor Protein

**Definition:** An endogenous 105-kDa plasma glycoprotein produced primarily by the LIVER and MONOCYTES. It inhibits a broad spectrum of proteases, including the COMPLEMENT C1R and the COMPLEMENT C1S proteases of the CLASSICAL COMPLEMENT PATHWAY, and the MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES. C1-INH-deficient individuals suffer from HEREDITARY ANGIOEDEMA TYPES I AND II.

**Tree numbers:** - D09.400.430.780 - D12.644.861.140.500 - D12.776.124.486.274.920.250.500 - D12.776.395.320 - D12.776.872.140.500

**Synonyms:** - C1 Esterase Inhibitor - C1-Inhibitor Protein - C1-INH Protein - Plasma Protease C1 Inhibitor - Complement C1-Inhibitor Protein - Serpin G1 - Serpin Family G Member 1 - SERPING1