D050720Level 6
Retinoblastoma-Like Protein p107
**Definition:** A negative regulator of the CELL CYCLE that undergoes PHOSPHORYLATION by CYCLIN-DEPENDENT KINASES. It contains a conserved pocket region that binds E2F4 TRANSCRIPTION FACTOR and interacts with viral ONCOPROTEINS such as POLYOMAVIRUS TUMOR ANTIGENS; ADENOVIRUS E1A PROTEINS; and PAPILLOMAVIRUS E7 PROTEINS.
**Tree numbers:** - D12.776.624.776.717 - D12.776.660.770 - D12.776.744.747
**Synonyms:** - Retinoblastoma Like Protein p107 - Retinoblastoma-Like Protein 1 - p107 Tumor Suppressor Protein - RBL1 Protein
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