Dihydrouracil Dehydrogenase (NAD+)

**Definition:** An enzyme that catalyzes the oxidation of 5,6-dihydrouracil to URACIL using NAD as a cofactor. This enzyme also plays a role in the catabolism of the antimetabolite 5-FLUOROURACIL.

**Tree numbers:** - D08.811.682.660.325

**Synonyms:** - Dihydrothymine Dehydrogenase (NAD) - Dihydrouracil Dehydrogenase - Dihydrouracil Dehydrogenase (NAD)