Stathmin

**Definition:** A ubiquitous phosphoprotein that serves as an intracellular substrate for a variety of SIGNAL TRANSDUCTION PATHWAYS. PHOSPHORYLATION of stathmin occurs during CELL CYCLE progression, and stathmin functions as a microtubule-destabilizing protein that promotes MICROTUBULE depolymerization during INTERPHASE and late MITOSIS. Stathmin is expressed at very high levels in a variety of human CANCERS.

**Tree numbers:** - D12.776.220.600.450.480 - D12.776.624.664.700.957 - D12.776.744.772

**Synonyms:** - Phosphoprotein p18 - Phosphoprotein p19 - Prosolin - Lap18 Protein - Leukemia-Associated Phosphoprotein p18 - Metablastin - Op18 Phosphoprotein - Oncoprotein 18