D050803Level 7
Leucine Dehydrogenase
**Definition:** An octameric enzyme belonging to the superfamily of amino acid dehydrogenases. Leucine dehydrogenase catalyzes the reversible oxidative deamination of L-LEUCINE, to 4-methyl-2-oxopentanoate (2-ketoisocaproate) and AMMONIA, with the corresponding reduction of the cofactor NAD+.
**Tree numbers:** - D08.811.682.664.500.724
**Synonyms:** - L-Leucine Dehydrogenase - Leucine (Branched-Chain Amino Acid) Dehydrogenase
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