Interferon-Stimulated Gene Factor 3

**Definition:** A multimeric complex that functions as a ligand-dependent transcription factor. ISGF3 is assembled in the CYTOPLASM and translocated to the CELL NUCLEUS in response to INTERFERON signaling. It consists of ISGF3-GAMMA and ISGF3-ALPHA, and it regulates expression of many interferon-responsive GENES.

**Tree numbers:** - D12.644.360.024.303 - D12.776.157.057.061 - D12.776.260.513 - D12.776.476.024.386 - D12.776.930.354

**Synonyms:** - ISGF3 Factor - Transcription Factor ISGF3 - IFN-Stimulated Gene Factor 3 Complex - ISGF3 Transcription Factor