Glycine Dehydrogenase (Decarboxylating)

**Definition:** A PYRIDOXAL PHOSPHATE dependent enzyme that catalyzes the decarboxylation of GLYCINE with the transfer of an aminomethyl group to the LIPOIC ACID moiety of the GLYCINE DECARBOXYLASE COMPLEX H-PROTEIN. Defects in P-protein are the cause of non-ketotic hyperglycinemia. It is one of four subunits of the glycine decarboxylase complex.

**Tree numbers:** - D05.500.562.452.200 - D08.811.600.391.200 - D08.811.682.664.500.498.500

**Synonyms:** - Glycine Cleavage System P-Protein - Glycine Decarboxylase - Glycine Decarboxylase Complex P-Protein - P-protein, Glycine Decarboxylase