1-Pyrroline-5-Carboxylate Dehydrogenase

**Definition:** An enzyme that catalyzes the oxidation of 1-pyrroline-5-carboxylate to L-GLUTAMATE in the presence of NAD. Defects in the enzyme are the cause of hyperprolinemia II.

**Tree numbers:** - D08.811.682.662.693

**Synonyms:** - GGS Dehydrogenase - NADP+ Specific 8-Glutamate Semialdehyde Dehydrogenase - Delta(1)-Pyrroline-5-Carboxylate Dehydrogenase - Glutamic-Gamma-Semialdehyde Dehydrogenase - Glutamyl-Gamma-Semialdehyde Dehydrogenase