Synaptotagmin II

**Definition:** A vesicular transport protein that was originally characterized as an inositol polyphosphate binding protein. Synaptotagmin II helps regulate EXOCYTOSIS of SYNAPTIC VESICLES and appears to serve as a calcium sensor to trigger NEUROTRANSMITTER release. It also acts as a nerve cell receptor for certain BOTULINUM TOXINS.

**Tree numbers:** - D12.776.157.125.825.500 - D12.776.543.990.850.500

**Synonyms:** - Synaptotagmin 2