Voltage-Dependent Anion Channels

**Definition:** A family of voltage-gated eukaryotic porins that form aqueous channels. They play an essential role in mitochondrial CELL MEMBRANE PERMEABILITY, are often regulated by BCL-2 PROTO-ONCOGENE PROTEINS, and have been implicated in APOPTOSIS.

**Tree numbers:** - D12.776.157.530.400.500.520 - D12.776.543.550.450.730.520 - D12.776.543.585.400.730.520

**Synonyms:** - Voltage-Dependent Anion Channel - Pore Forming Protein VDAC - Voltage-Dependent, Anion-Selective Channels - VDAC Proteins