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D051027Level 7

Phosphoribosylaminoimidazolecarboxamide Formyltransferase

**Definition:** An enzyme that catalyzes the conversion of aminoimidazole-4-carboxamide ribonucleotide to 5-formyl-aminoimidazole-4-carboxamide ribonucleotide in the purine de novo synthesis pathway. It requires the cofactor N(10)-FORMYLTETRAHYDROFOLATE as the formyl donor.

**Tree numbers:** - D08.811.913.555.400.625

**Synonyms:** - Aminoimidazolecarboxamide Ribonucleotide Transformylase - AICAR Formyltransferase - AICAR Transformylase - AICARTFase

GET/api/v1/systems/mesh/nodes/D051027
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