Proto-Oncogene Proteins c-ret

**Definition:** Receptor protein-tyrosine kinases involved in the signaling of GLIAL CELL-LINE DERIVED NEUROTROPHIC FACTOR ligands. They contain an extracellular cadherin domain and form a receptor complexes with GDNF RECEPTORS. Mutations in ret protein are responsible for HIRSCHSPRUNG DISEASE and MULTIPLE ENDOCRINE NEOPLASIA TYPE 2.

**Tree numbers:** - D08.811.913.696.620.682.725.400.087 - D09.400.430.890.200.188.500 - D12.776.395.550.200.188.500 - D12.776.476.568.400.087 - D12.776.543.131.500 - D12.776.543.750.630.217 - D12.776.624.664.700.194

**Synonyms:** - Receptor Tyrosine Kinase RET - Proto-Oncogene Protein Ret - Proto-Oncogene Protein c-ret - ret Proto-Oncogene Proteins - c-ret Protein