Toll-Like Receptors

**Definition:** A family of pattern recognition receptors characterized by an extracellular leucine-rich domain and a cytoplasmic domain that share homology with the INTERLEUKIN 1 RECEPTOR and the DROSOPHILA toll protein. Following pathogen recognition, toll-like receptors recruit and activate a variety of SIGNAL TRANSDUCING ADAPTOR PROTEINS.

**Tree numbers:** - D12.776.543.750.705.910.500

**Synonyms:** - Receptors, Toll-Like - Toll-Like Receptor