D051339Level 6
Actin Depolymerizing Factors
**Definition:** A family of low MOLECULAR WEIGHT actin-binding proteins found throughout eukaryotes. They remodel the actin CYTOSKELETON by severing ACTIN FILAMENTS and increasing the rate of monomer dissociation.
**Tree numbers:** - D05.750.078.730.212 - D12.776.220.525.212
**Synonyms:** - Actin Depolymerizing Protein - Cofilin - ADF Proteins (Actin Depolymerizing Factors) - Cofilin Proteins - Cofilins - Actin Depolymerizing Proteins
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