Cortactin

**Definition:** A microfilament protein that interacts with F-ACTIN and regulates cortical actin assembly and organization. It is also an SH3 DOMAIN containing phosphoprotein, and it mediates tyrosine PHOSPHORYLATION based SIGNAL TRANSDUCTION by PROTO-ONCOGENE PROTEIN PP60(C-SRC).

**Tree numbers:** - D05.750.078.730.281 - D12.644.360.024.280 - D12.776.157.057.014 - D12.776.220.525.281 - D12.776.476.024.311 - D12.776.744.390