Cyclin-Dependent Kinase 4

**Definition:** Cyclin-dependent kinase 4 is a key regulator of G1 PHASE of the CELL CYCLE. It partners with CYCLIN D to phosphorylate RETINOBLASTOMA PROTEIN. CDK4 activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P16.

**Tree numbers:** - D08.811.913.696.620.682.700.646.500.875 - D12.776.167.200.451 - D12.776.476.563.646.500.875

**Synonyms:** - Cyclin D-Dependent Kinase CDK4 - p34PSK-J3 Kinase - Cell Division Protein Kinase 4 - Cdk4 Protein Kinase - PSK-J3 Kinase - Cdk4 Protein - Cdk4 Cyclin-Dependent Kinase