Aquaporin 2

**Definition:** Aquaporin 2 is a water-specific channel protein that is expressed in KIDNEY COLLECTING DUCTS. The translocation of aquaporin 2 to the apical PLASMA MEMBRANE is regulated by VASOPRESSIN, and MUTATIONS in AQP2 have been implicated in a variety of kidney disorders including DIABETES INSIPIDUS.

**Tree numbers:** - D12.776.157.530.400.500.040.437 - D12.776.543.550.450.730.040.437 - D12.776.543.585.400.730.040.530

**Synonyms:** - Aquaporin-2 - Aquaporin-CD - Water Channel Of Collecting Duct - AQP2 Protein