Paxillin

**Definition:** Paxillin is a signal transducing adaptor protein that localizes to FOCAL ADHESIONS via its four LIM domains. It undergoes PHOSPHORYLATION in response to integrin-mediated CELL ADHESION, and interacts with a variety of proteins including VINCULIN; FOCAL ADHESION KINASE; PROTO-ONCOGENE PROTEIN PP60(C-SRC); and PROTO-ONCOGENE PROTEIN C-CRK.

**Tree numbers:** - D12.644.360.024.316 - D12.776.157.057.092 - D12.776.476.024.397 - D12.776.512.374 - D12.776.744.665