Receptor, Fibroblast Growth Factor, Type 2

**Definition:** A fibroblast growth factor receptor which contains three extracellular IMMUNOGLOBULIN I-SET DOMAINS and is expressed as two isoforms. One receptor isoform is expressed in the MESENCHYME and is activated by FIBROBLAST GROWTH FACTOR 2. A second isoform is expressed mainly by EPITHELIAL CELLS and is activated by FIBROBLAST GROWTH FACTOR 7 and FIBROBLAST GROWTH FACTOR 10. Mutation of the gene for fibroblast growth factor receptor 2 can result in craniosynostotic syndromes (e.g., APERT SYNDROME; and CROUZON SYNDROME).

**Tree numbers:** - D08.811.913.696.620.682.725.400.178 - D12.776.476.568.400.178 - D12.776.543.750.630.441 - D12.776.543.750.750.400.370.750

**Synonyms:** - BEK Fibroblast Growth Factor Receptor - BEK Protein Tyrosine Kinase - Bek Fgf Receptor Kinase - BEK Fibroblast Growth Factor Receptor Kinase - CD332 Antigen - Bek-Related Fibroblast Growth Factor-Receptor-1 - Fibroblast Growth Factor Receptors 2 - FGFR2 Protein - Fibroblast Growth Factor Receptor 2