I-kappa B Kinase

**Definition:** A protein serine-threonine kinase that catalyzes the PHOSPHORYLATION of I KAPPA B PROTEINS. This enzyme also activates the transcription factor NF-KAPPA B and is composed of alpha and beta catalytic subunits, which are protein kinases and gamma, a regulatory subunit.

**Tree numbers:** - D08.811.913.696.620.682.700.494 - D12.776.476.563.494

**Synonyms:** - NK-kappa B-Activating Kinase NAK - IkappaB Kinase - I kappa B Kinase