Complement C5 Convertase, Alternative Pathway

**Definition:** A serine protease that cleaves multiple COMPLEMENT C5 into COMPLEMENT C5A (anaphylatoxin) and COMPLEMENT C5B in the ALTERNATIVE COMPLEMENT ACTIVATION PATHWAY. It is the complex of ALTERNATIVE PATHWAY C3 CONVERTASE (C3bBb) with an additional COMPLEMENT C3B, or C3bBb3b.

**Tree numbers:** - D12.776.124.486.274.045.387.500.750

**Synonyms:** - Alternative Pathway C5 Convertase - C5 Convertase (C3bBb3b) - C5 Convertase, Alternative Pathway