Protein Kinase C-alpha

**Definition:** A cytoplasmic serine threonine kinase involved in regulating CELL DIFFERENTIATION and CELLULAR PROLIFERATION. Overexpression of this enzyme has been shown to promote PHOSPHORYLATION of BCL-2 PROTO-ONCOGENE PROTEINS and chemoresistance in human acute leukemia cells.

**Tree numbers:** - D08.811.913.696.620.682.700.725.100 - D12.776.476.563.725.100

**Synonyms:** - Protein Kinase C(alpha) - Protein Kinase C alpha - PKC-alpha Serine-Threonine Kinase